Poison - Double Dose: Ultimate Hits is a double disc greatest hits compilation album released May 3, 2011 by the hard rock band Poison to celebrate the band's 25th anniversary. The career-spanning collection features thirty-five of the multi-platinum band's top hits and fan favorites. The album charted at #23 on the Billboard Top Hard Rock Albums chart and #17 in Canada.

Poison is an American glam metal band formed in 1983 in Mechanicsburg, Pennsylvania. The most successful incarnation of the band consists of lead singer and rhythm guitarist Bret Michaels, drummer Rikki Rockett, lead guitarist and backing vocalist C.C. DeVille, and bassist Bobby Dall. The band achieved huge commercial success in the mid-1980s through the mid-1990s and has sold 30 million records in the United States and over 65 million albums worldwide.