Downtown Albuquerque is the central business district of Albuquerque, New Mexico, United States. It is where a significant number of the city's highrise buildings are located, and is the center of government and business for the Greater Albuquerque metropolitan region.

Albuquerque, also known as ABQ, Burque, and the Duke City, is the most populous city in the U.S. state of New Mexico. Founded in 1706 as La Villa de Alburquerque by Santa Fe de Nuevo México governor Francisco Cuervo y Valdés, and named in honor of Francisco Fernández de la Cueva, 10th Duke of Alburquerque and Viceroy of New Spain, it served as an outpost on El Camino Real linking Mexico City to the northernmost territories of New Spain.