Downtown Detroit is the central business district and a residential area of the city of Detroit, Michigan, United States. Locally, downtown tends to refer to the 1.4 square mile region bordered by M-10 to the west, Interstate 75 to the north, I-375 to the east, and the Detroit River to the south. Although, it may also refer to the Greater Downtown area, a 7.2 square mile region that includes surrounding neighborhoods such as Midtown, Corktown, Rivertown, and Woodbridge.

M-10 is a state trunkline highway in the Metro Detroit area of Michigan in the United States. Nominally labeled north-south, the route follows a northwest-southeast alignment. The southernmost portion follows Jefferson Avenue in downtown Detroit, and the southern terminus is at the intersection of Jefferson and M-3 next to the entrance to the Detroit–Windsor Tunnel. The northern terminus is in West Bloomfield Township at the intersection with Orchard Lake Road. The highway has several names as it runs through residential and commercial areas of the west side of Detroit and into the suburb of Southfield. It is called the John C. Lodge Freeway, James Couzens Highway, and Northwestern Highway. One segment has also been named the Aretha Franklin Memorial Highway.