Downtown Los Angeles (DTLA) is the central business district of Los Angeles. It is part of the Central Los Angeles region and covers a 5.84 sq mi (15.1 km2) area. As of 2020, it contains over 500,000 jobs and has a population of roughly 85,000 residents, with an estimated daytime population of over 200,000 people prior to the COVID-19 pandemic. Despite a business exodus from downtown Los Angeles since the COVID-19 pandemic, the district is evolving as a cultural center with the world's largest showcase of architecture designed by Frank Gehry.

Los Angeles, often referred to by its initials L.A., is the most populous city in the U.S. state of California. With roughly 3.9 million residents within the city limits as of 2020, Los Angeles is the second-most populous city in the United States, behind only New York City; it is also the commercial, financial and cultural center of Southern California. Los Angeles has an ethnically and culturally diverse population, and is the principal city of a metropolitan area of 13.2 million people. Greater Los Angeles, which includes the Los Angeles and Riverside–San Bernardino metropolitan areas, is a sprawling metropolis of over 18 million residents.