The Downtown Morgantown Historic District is a federally designated historic district in Morgantown, Monongalia County, West Virginia. The district, encompassing approximately 75 acres, has 122 contributing buildings and 2 contributing sites including commercial and public buildings, residences, and churches. The district has been listed on the National Register of Historic Places since May 2, 1996. Ten of the contributing buildings are listed separately on the National Register of Historic Places. Significant structures located within the historic district are the Monongalia County Courthouse, the Metropolitan Theater, and the Old Morgantown Post Office.

Morgantown is a city in and the county seat of Monongalia County, West Virginia, United States, situated along the Monongahela River. The most populous city in North Central West Virginia and the third-most populous city in the state, Morgantown is best known as the home of West Virginia University. The population was 30,347 at the 2020 census. The city serves as the anchor of the Morgantown metropolitan area, which had a population of 138,176 in 2020.