Downtown San Bernardino is a district in the city of San Bernardino, California, in San Bernardino County, United States. It is home to city and county government buildings, and to the city's central business district. The downtown area of San Bernardino is home to multiple diplomatic missions for the Inland Empire, being one of only four California cities with multiple consulates. The governments of Guatemala and Mexico have established their consulates in the civic center. Downtown San Bernardino is bounded by I-215 to the west, Waterman Avenue to the east, Baseline Street to the north, and Mill Street to the south.

San Bernardino is a city and county seat of San Bernardino County, California, United States. Located in the Inland Empire region of Southern California, the city had a population of 222,101 in the 2020 census, making it the 18th-largest city in California. San Bernardino is the economic, cultural, and political hub of the San Bernardino Valley and the Inland Empire. The governments of El Salvador, Guatemala, and Mexico have established the metropolitan area's only consulates in the downtown area of the city. Additionally, San Bernardino serves as an anchor city to the 3rd largest metropolitan area in California and the 12th largest metropolitan area in the United States; the San Bernardino-Riverside MSA.