Dr. Jekyll and Mr. Hyde is a 1920 American silent horror film produced by Famous Players–Lasky and released through Paramount/Artcraft. The film, which stars John Barrymore, is an adaptation of the 1886 novella Strange Case of Dr Jekyll and Mr Hyde by Robert Louis Stevenson. John S. Robertson directed the production, and Clara Beranger wrote the screenplay, based on the 1887 stage play by Thomas Russell Sullivan that in turn was based on the novel.

John Barrymore was an American actor on stage, screen, and radio. A member of the Drew and Barrymore theatrical families, he initially tried to avoid the stage, and briefly attempted a career as an artist, but appeared on stage together with his father Maurice in 1900, and then his sister Ethel the following year. He began his career in 1903 and first gained attention as a stage actor in light comedy, then high drama, culminating in productions of Justice (1916), Richard III (1920), and Hamlet (1922); his portrayal of Hamlet led to him being called the "greatest living American tragedian".