Dragon Quest V: Hand of the Heavenly Bride is a role-playing video game and the fifth installment in the Dragon Quest video game series, second of the Zenithian Trilogy. Originally developed by Chunsoft and published by Enix Corporation, Dragon Quest V was the first title in the series to be released for the Super Famicom video game console in Japan in September 1992. Dragon Quest V was the first game in the series to not be released in America due to programming issues at the time.

Dragon Quest, previously published as Dragon Warrior in North America until 2005, is a series of role-playing games created by Japanese game designers Armor Project, Bird Studio and Sugiyama Kobo to its publisher Enix, with all of the involved parties co-owning the copyright of the series since then. The games are published by Square Enix since its inception, with localized remakes and ports of later installments for the Nintendo DS, Nintendo 3DS, and Nintendo Switch being published by Nintendo outside of Japan. With its first game published in 1986, there are eleven main-series games, along with numerous spin-off games. In addition, there have been numerous manga, anime and novels published under the franchise, with nearly every game in the main series having a related adaptation.