The Dublin–Cork Main Line is the main InterCity railway route in Ireland between Dublin Heuston and Cork Kent. In 2018, 3.46 million passengers travelled on the line, a 10% increase from 2017 figures.

Heuston Station, also known as Dublin Heuston, is one of Dublin's largest railway stations and links the capital with the south, southwest and west of Ireland. It is operated by Iarnród Éireann (IÉ), the national railway operator. It also houses the head office of its parent company, Córas Iompair Éireann (CIÉ). The station is named in honour of Seán Heuston, an executed leader of the 1916 Easter Rising, who had worked in the station's offices.