Dudleya guadalupensis is a very rare species of succulent perennial plant in the family Crassulaceae commonly known as the Guadalupe liveforever. It is a rosette-forming leaf succulent, with foliage that is variously colored light green, green, and a waxy white. It is characterized by dense leaves that fold over the center in dormancy, a curving, sinuous flower stalk, and white, cup-shaped flowers. It is endemic to the rocks and islets off of Guadalupe Island, an isolated volcanic island in the Pacific Ocean located 241 kilometers off of the coast of Baja California.

Guadalupe Island is a volcanic island located 241 kilometres off the western coast of Mexico's Baja California Peninsula and about 400 km (200 nmi) southwest of the city of Ensenada in the state of Baja California, in the Pacific Ocean. The various volcanoes are extinct or dormant. In 2005 Guadalupe Island and its surrounding waters and islets were declared a biosphere reserve to restore its vegetation and to protect its population of marine mammals and birds. The island is a popular destination for great white shark cage diving. Guadalupe Island is inhabited only by scientists, military personnel operating a weather station, and a small group of seasonal fishermen. The island is mostly arid and has very little surface water.