The Duke’s Mayo Bowl is an annual college football bowl game that has been played at Bank of America Stadium in Charlotte, North Carolina, since 2002. Originally commissioned as the Queen City Bowl, it has undergone many name changes due to sponsorship rights. The game currently features a matchup between a team from the Atlantic Coast Conference (ACC) and a team from the Southeastern Conference (SEC), the Big Ten Conference or the Big 12 Conference.

Bank of America Stadium is a 74,867-seat multi-purpose stadium located on 33 acres (13 ha) in uptown Charlotte, North Carolina, United States. It is the home facility and headquarters of the Carolina Panthers of the National Football League and Charlotte FC of Major League Soccer. The stadium opened in 1996 as Ericsson Stadium, with Swedish telecom company LM Ericsson initially holding the naming rights. In 2004, Charlotte-based financial services company Bank of America purchased the naming rights under a 20-25-year agreement at $140 million. Former Panthers president Danny Morrison called it a "classic American stadium" due to its bowl design and other features.