The Duke–NUS Medical School (Duke–NUS) is a graduate medical school in Singapore. The school was set up in April 2005 as the Duke–NUS Graduate Medical School, Singapore's second medical school, after the Yong Loo Lin School of Medicine, and before the Lee Kong Chian School of Medicine. It is a collaboration between Duke University in the United States and the National University of Singapore in Singapore. Duke-NUS follows the American model of post-baccalaureate medical education, in which students begin their medical studies after earning a bachelor's degree. Students are awarded degrees from both Duke University and the National University of Singapore.

Doctor of Medicine is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery (M.B.B.S.) was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Ireland and other countries, the M.D. is a research doctorate, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others' usage of M.D. is still typically titled Bachelor of Medicine, Bachelor of Surgery.