The Duke of York's Headquarters is a building in Chelsea in the Royal Borough of Kensington and Chelsea, England. In 1969 it was declared a listed building at Grade II*, due to its outstanding historic or architectural special interest.

Chelsea is an affluent area in West London, England, due south-west of Charing Cross by approximately 2.5 miles. It lies on the north bank of the River Thames and for postal purposes is part of the south-western postal area.