Duncanrig Secondary School is a secondary school within the town of East Kilbride in the South Lanarkshire council area in Scotland. The original building was designed in 1953 by the Scottish architect Basil Spence.

East Kilbride is the largest town in South Lanarkshire in Scotland, and the country's sixth-largest locality by population. It was also designated Scotland's first new town on 6 May 1947. The area lies on a raised plateau to the south of the Cathkin Braes, about eight miles southeast of Glasgow and close to the boundary with East Renfrewshire.