Duplin County is a county located in the U.S. state of North Carolina. As of the 2020 census, the population was 48,715. Its county seat is Kenansville.

Kenansville is a town in Duplin County, North Carolina, United States. Its population was 770 at the 2020 census. It is the county seat of Duplin County. The town was named for James Kenan, a member of the North Carolina Senate. Liberty Hall, his early 1800s era historic home, is located within Kenansville.