A dwarf cat is a domestic cat with dwarfism due to rare genetic mutations causing a disproportionate feline body and significant health problems. Unlike undersized cats of normal proportions, dwarf cats suffer from the genetic mutations osteochondrodysplasia and achondroplasia. These genetic disorders of bone and cartilage are typically manifested as abnormal bone shape, poor growth or lack of growth, bowing of the limbs to the side – front legs are more likely to be affected, and spinal malformations.

Tardar Sauce, nicknamed Grumpy Cat, was an American internet celebrity cat. She was known for her permanently "grumpy" facial appearance, which was caused by an underbite and feline dwarfism. She came to prominence when a photograph of her was posted on September 22, 2012, on social news website Reddit by Bryan Bundesen, the brother of her owner Tabatha Bundesen. "Lolcats" and parodies created from the photograph by Reddit users became popular. She was the subject of a popular Internet meme in which humorously negative, cynical images were made from photographs of her.