Ešarra-ḫammat was a queen of the Neo-Assyrian Empire as the primary consort of Esarhaddon. Ešarra-ḫammat had been married to Esarhaddon for over a decade by the time he became king, having married him c. 695 BC. Few sources from Ešarra-ḫammat's lifetime that mention her are known and she is thus chiefly known from sources dating to after her death in February 672 BC, an event which deeply affected Esarhaddon. Esarhaddon had a great mausoleum constructed for her, unusual for burials of Assyrian queens, and had her death recorded in the Babylonian Chronicles. Ešarra-ḫammat might have been the mother of Esarhaddon's most prominent children, i.e. the daughter Šērūʾa-ēṭirat and the sons Ashurbanipal and Shamash-shum-ukin.

Naqiʾa or Naqia (Akkadian: Naqīʾa, also known as Zakūtu, was a wife of the Assyrian king Sennacherib and the mother of his son and successor Esarhaddon. Naqiʾa is the best documented woman in the history of the Neo-Assyrian Empire and she reached an unprecedented level of prominence and public visibility; she was perhaps the most influential woman in Assyrian history. She is one of the few ancient Assyrian women to be depicted in artwork, to commission her own building projects, and to be granted laudatory epithets in letters by courtiers. She is also the only known ancient Assyrian figure other than kings to write and issue a treaty.