Ešarra-ḫammat was a queen of the Neo-Assyrian Empire as the primary consort of Esarhaddon. Ešarra-ḫammat had been married to Esarhaddon for over a decade by the time he became king, having married him c. 695 BC. Few sources from Ešarra-ḫammat's lifetime that mention her are known and she is thus chiefly known from sources dating to after her death in February 672 BC, an event which deeply affected Esarhaddon. Esarhaddon had a great mausoleum constructed for her, unusual for burials of Assyrian queens, and had her death recorded in the Babylonian Chronicles. Ešarra-ḫammat might have been the mother of Esarhaddon's most prominent children, i.e. the daughter Šērūʾa-ēṭirat and the sons Ashurbanipal and Shamash-shum-ukin.

Šērūʾa-ēṭirat, called Saritrah in later Aramaic texts), was an ancient Assyrian princess of the Sargonid dynasty, the eldest daughter of Esarhaddon and the older sister of his son and successor Ashurbanipal. She is the only one of Esarhaddon's daughters to be known by name and inscriptions listing the royal children suggest that she outranked several of her brothers, such as her younger brother Aššur-mukin-paleʾa, but ranked below the crown princes Ashurbanipal and Shamash-shum-ukin. Her importance could be explained by her possibly being the oldest of all Esarhaddon's children.