E. 1999 Eternal is the second studio album by American hip hop group Bone Thugs-N-Harmony, released July 25, 1995, on Ruthless Records. The album was released four months after the death of rapper Eazy-E, the group's mentor and the executive producer of the album. Both the album and single "Tha Crossroads" are dedicated to him. Following up on the surprise success of their breakthrough single "Thuggish Ruggish Bone", it became a popular album and received positive reviews from music critics, earning praise for the group's melodic rapping style. The album title is a portmanteau of Cleveland's eastside neighborhood centering on East 99th Street and St. Clair Avenue where the group is based and the then-future year 1999.

Bone Thugs-n-Harmony is an American hip hop group composed of rappers Bizzy Bone, Wish Bone, Layzie Bone, Krayzie Bone, and Flesh-n-Bone. Formed in 1991 in Cleveland, Ohio, the group signed to fellow American rapper Eazy-E's Ruthless Records in late 1993, on which they debuted with their EP Creepin on ah Come Up the next year. The EP included their breakout hit single "Thuggish Ruggish Bone". In 1995, the group released its second album E. 1999 Eternal, which included hits "1st of tha Month" and "East 1999". Their hit song "Tha Crossroads", a tribute to then-recently deceased mentor Eazy-E, won a Grammy Award in 1997.