The first season of the American fictional drama television series ER aired from September 19, 1994 to May 18, 1995. This season, containing 25 episodes, is the longest running of the series.

ER is an American medical drama television series created by Michael Crichton that aired on NBC from September 19, 1994, to April 2, 2009, with a total of 331 episodes spanning 15 seasons. It was produced by Constant c Productions and Amblin Television, in association with Warner Bros. Television. ER follows the inner life of the emergency room (ER) of Cook County General Hospital in Chicago, and various critical issues faced by the department's physicians and staff.