The E Line is a 22-mile (35 km) light rail line in Los Angeles County, California. It is one of the six lines of the Los Angeles Metro Rail system, operated by the Los Angeles County Metropolitan Transportation Authority (Metro). The E Line runs east-west and serves 29 stations between East Los Angeles and Santa Monica. It interlines and shares five stations with the A Line in Downtown Los Angeles. Service operates for approximately 19 hours with headways of up to 8 minutes during peak hours. The E Line, the second-busiest light rail line in the system, saw an average of 41,902 passengers on weekdays in October 2023.

The Los Angeles Metro Rail is an urban rail transit system serving Los Angeles County, California in the United States. It consists of six lines: four light rail lines and two rapid transit lines, serving a total of 101 stations. It connects with the Metro Busway bus rapid transit system, the Metrolink commuter rail system, as well as several Amtrak lines. Metro Rail is owned and operated by the Los Angeles County Metropolitan Transportation Authority (Metro).