East Carolina University (ECU) is a public university in Greenville, North Carolina, United States. It is the fourth largest university in North Carolina and the only one in the state with both a medical school and a dental school.

Greenville is the county seat and most populous city of Pitt County, North Carolina, United States. It is the principal city of the Greenville, NC Metropolitan Statistical Area, and the 12th-most populous city in North Carolina. Greenville is the health, entertainment, and educational hub of North Carolina's Tidewater and Coastal Plain. As of the 2020 census, there were 87,521 people in the city. The city has continued to see a population increase with a majority of the influx being seen during the 20th and early 21st centuries.