The East Ferry Avenue Historic District is a historic residential district in Midtown Detroit, Michigan. The nationally designated historic district stretches two blocks from Woodward Avenue east to Brush Street; the locally designated historic district includes a third block between Brush and Beaubien. The district includes the separately designated Col. Frank J. Hecker House and the Charles Lang Freer House. It was designated a Michigan State Historic Site in 1976 and listed on the National Register of Historic Places in 1980.

Midtown Detroit is a commercial and residential district located along the east and west side of Woodward Avenue, north of Downtown Detroit, and south of the New Center area. The area includes several historic districts. In addition, it contains a residential area of some 14,550 people and covers 2.09 sq mi. The community area of neighborhoods is bounded by the Chrysler Freeway (I-75) on the east, the Lodge Freeway (M-10) on the west, the Edsel Ford Freeway (I-94) on the north, and the Fisher Freeway (I-75) on the south.