East Khasi Hills is an administrative district in the state of Meghalaya in India. The district headquarters are located at Shillong. The district occupies an area of 2,748 km² and has a population of 825,922. As of 2011, it is the most populous district of Meghalaya's 12 districts.

Meghalaya is a state in northeast India. Meghalaya was formed on 21 January 1972 by carving out two districts from the state of Assam: (a) the United Khasi Hills and Jaintia Hills and (b) the Garo Hills. The estimated population of Meghalaya in 2014 was 3,211,474. Meghalaya covers an area of approximately 22,429 square kilometres, with a length-to-breadth ratio of about 3:1.