East Otto is a town in Cattaraugus County, New York, United States. The population was 977 at the 2020 census. The town, along with neighboring Otto, is named after an agent of the Holland Land Company, Jacob Otto. The town of East Otto is on the northern border of the county.

Cattaraugus County is a county in Western New York, with one side bordering Pennsylvania. As of the United States 2020 census, the population was 77,042. The county seat is Little Valley. The county was created in 1808 and later organized in 1817. The county is part of the Western New York region of the state.