Edgar Allan Poe was an American writer and literary critic. Poe is best known for his poetry and short stories his tales of mystery and the macabre, he is regarded as a central figure of Romanticism in the United States and of American literature as a whole, he was one of the country's earliest practitioners of the short story. He is considered the inventor of the detective fiction genre and is further credited with contributing to the emerging genre of science fiction, he was the first well-known American writer to earn a living through writing alone, resulting in a financially difficult life and career. Poe was born in the second child of actors David and Elizabeth "Eliza" Arnold Hopkins Poe, his father abandoned the family in 1810, his mother died the following year. Thus orphaned, the child was taken in by Frances Allan of Richmond, Virginia, they never formally adopted him. Tension developed as John Allan and Edgar Poe clashed over debts, including those incurred by gambling, the cost of Poe's secondary education.

He left after a year due to lack of money. Edgar Poe quarreled with John Allan over the funds for his education and enlisted in the Army in 1827 under an assumed name, it was at this time that his publishing career began with the anonymous collection Tamerlane and Other Poems, credited only to "a Bostonian". Edgar Poe and John Allan reached a temporary rapprochement after the death of Frances Allan in 1829. Poe failed as an officer cadet at West Point, declaring a firm wish to be a poet and writer, he parted ways with John Allan. Poe switched his focus to prose and spent the next several years working for literary journals and periodicals, becoming known for his own style of literary criticism, his work forced him to move among several cities, including Baltimore and New York City. He married his 13-year-old cousin, Virginia Clemm, in 1836. In January 1845, Poe published his poem "The Raven" to instant success, but Virginia died of tuberculosis two years after its publication. Poe planned for years to produce his own journal The Penn, but before it could be produced, he died in Baltimore on October 7, 1849, at age 40.

The cause of his death is unknown and has been variously attributed to alcohol, "brain congestion", drugs, heart disease, suicide and other causes. Poe and his works influenced literature around the world, as well as specialized fields such as cosmology and cryptography, he and his work appear throughout popular culture in literature, music and television. A number of his homes are dedicated museums today; the Mystery Writers of America present an annual award known as the Edgar Award for distinguished work in the mystery genre. He was born Edgar Poe in Boston on January 19, 1809, the second child of English-born actress Elizabeth Arnold Hopkins Poe and actor David Poe Jr, he had an elder brother named a younger sister named Rosalie Poe. Their grandfather David Poe Sr. emigrated from County Cavan, Ireland around 1750. Edgar may have been named after a character in William Shakespeare's King Lear which the couple were performing in 1809, his father abandoned the family in 1810, his mother died a year from consumption.

Poe was taken into the home of John Allan, a successful merchant in Richmond, Virginia who dealt in a variety of goods, including tobacco, wheat and slaves. The Allans served as a foster family and gave him the name "Edgar Allan Poe", though they never formally adopted him; the Allan family had Poe baptized in the Episcopal Church in 1812. John Allan alternately spoiled and aggressively disciplined his foster son; the family sailed to Britain in 1815, Poe attended the grammar school for a short period in Irvine, Scotland before rejoining the family in London in 1816. There he studied at a boarding school in Chelsea until summer 1817, he was subsequently entered at the Reverend John Bransby's Manor House School at Stoke Newington a suburb 4 miles north of London. Poe moved with the Allans back to Richmond, Virginia in 1820. In 1824, he served as the lieutenant of the Richmond youth honor guard as Richmond celebrated the visit of the Marquis de Lafayette. In March 1825, John Allan's uncle and business benefactor William Galt died, said to be one of the wealthiest men in Richmond, leaving Allan several acres of real estate.

The inheritance was estimated at $750,000. By summer 1825, Allan celebrated his expansive wealth by purchasing a two-story brick home named Moldavia. Poe may have become engaged to Sarah Elmira Royster before he registered at the University of Virginia in February 1826 to study ancient and modern languages; the university was in its infancy, established on the ideals of its founder Thomas Jefferson. It had strict rules against gambling, guns and alcohol, but these rules were ignored. Jefferson had enacted a system of student self-government, allowing students to choose their own studies, make their own arrangements for boarding, report all wrongdoing to the faculty; the unique system was still in chaos, there was a high dropout rate. During his time there, Poe lost touch with Royster and became estranged from his foster father over gambling debts, he claimed that Allan had not given him sufficient money to register for classes, purchase texts, procure and furnish a dormitory. Allan did send additional money and clothes.

He gave up on the university after

George Perry is the former Dean of the College of Sciences, Semmes Distinguished University Chair in Neurobiology, Chief Scientist of the Brain Health Consortium and Professor of Biology and Chemistry at the University of Texas at San Antonio. Perry is recognized in the field of Alzheimer's disease research for his work on oxidative stress. Perry received his Bachelor of Arts degree in Zoology from University of Santa Barbara. After graduation, he studied at Scripps Institution of Oceanography, Hopkins Marine Station of Stanford University, the Marine Biological Laboratory at Woods Hole. D from the University of California at San Diego in Marine Biology under David Epel in 1979, he received a postdoctoral fellowship in the Department of Cell Biology in the laboratories of William R. Brinkley, Joseph Bryan and Anthony R. Means at Baylor College of Medicine where he laid the foundation for his observations of cytoskeletal abnormalities. In 1982, Perry joined the faculty of Case Western Reserve University, where he holds an adjunct appointment.

He is dean of the College of Sciences and professor of biology at the University of Texas at San Antonio. He is distinguished as one of the top Alzheimer’s disease researchers with over 1000 publications, one of the top 100 most-cited scientists in Neuroscience & Behavior and one of the top 25 scientists in free radical research. Perry is cited and is recognized as an ISI cited researcher. Perry is editor for numerous journals. Several of the publishers, including Bentham Open, OMICS, Science Domain International and IOS Press, have been credibly identified as predatory. Perry is the current editor-in-chief of Letters in Drug Design & Discovery, a medicinal chemistry journal, published by Bentham Science Publishers. Perry is the current editor-in-chief for the Journal of Alzheimer's Disease, an international multidisciplinary journal that specialises in Alzheimer's disease. Perry is the editor-in-chief of several predatory open access journals; these include The Open Neurology Journal, published by Bentham Open, Journal of Cytology & Histology, published by OMICS Publishing Group and Annual Review & Research in Biology, published by ScienceDomain International.

All three publishers were listed on Beall's list of predatory publishers prior to its shut down in 2017. Perry is fellow of the American Association for the Advancement of Sciences, Microscopy Society of America, International Engineering and Technology Institute, Texas Academy of Sciences, past-president and interim executive director of the Southwestern and Rocky Mountain Division of American Association for the Advancement of Sciences, Chair of the Board of the National Organization of Portuguese Americans and past-president of the American Association of Neuropathologists. Perry's research is focused on the mechanism of formation and physiological consequences of the cytopathology of Alzheimer disease, he has played a key role in elucidating oxidative damage as the initial cytopathological abnormality in Alzheimer disease. He is working to determine the sequence of events leading to neuronal oxidative damage and the source of the increased oxygen radicals, his current studies focus on two issues: the metabolic basis for the mitochondrial damage restricted to vulnerable neurons.

Future Neurolology Interview Journal of Alzheimer's Disease UTSA Faculty Biography TEDXAlamo: Living with Aging on YouTube Science Watch Top 20 Alzheimer's Researchers PBS Interview Express-News Article

Christian Jason Bowman is an actor, director and screenwriter who has appeared in television shows and films including North Shore, Prison Break, Sin City: A Dame to Kill For. Bowman began his acting career on North Shore in 2004, he was cast as Steve Jenkins, a character seen on the first season of Lost. Bowman joined the cast of Prison Break as Agent King, The Lying Game and Sin City: A Dame to Kill For. Christian Bowman is a graduate from the Radio Television Film program at the University of Texas at Austin where he was the recipient of the Excellence in Producing award by the Longhorns Creative Foundation. While in Austin, TX, Bowman provided charity work for a Public Broadcasting Services television show as well as a Human Trafficking Awareness campaign with Mathew McConaughey with his production company Last Pull Productions. Christian Bowman on IMDb www.lastpullproductions.com www.christianbowman.com