The Poe Museum or the Edgar Allan Poe Museum, is a museum located in the Shockoe Bottom neighborhood of Richmond, Virginia, United States, dedicated to American writer Edgar Allan Poe. Though Poe never lived in the building, it serves to commemorate his time living in Richmond. The museum holds one of the world's largest collections of original manuscripts, letters, first editions, memorabilia and personal belongings. The museum also provides an overview of early 19th century Richmond, where Poe lived and worked. The museum features the life and career of Poe by documenting his accomplishments with pictures, relics, and verse, and focusing on his many years in Richmond.

Shockoe Bottom historically known as Shockoe Valley, is an area in Richmond, Virginia, just east of downtown, along the James River. Located between Shockoe Hill and Church Hill, Shockoe Bottom contains much of the land included in Colonel William Mayo's 1737 plan of Richmond, making it one of the city's oldest neighborhoods.