El Camino Real is a 600-mile (965-kilometer) commemorative route connecting the 21 Spanish missions in California, along with a number of sub-missions, four presidios, and three pueblos. Historically associated with the Calle Real which terminates in Mexico City, as the former capital of New Spain and the seat of royal power for Las Californias, its southern end in the modern U.S. state of California is at Mission San Diego de Alcalá and its northern terminus is at Mission San Francisco Solano.

The San Francisco Peninsula is a peninsula in the San Francisco Bay Area that separates San Francisco Bay from the Pacific Ocean. On its northern tip is the City and County of San Francisco. Its southern base is Los Altos, Mountain View, in Santa Clara County, south of Palo Alto and north of Sunnyvale and Los Altos. Most of the Peninsula is occupied by San Mateo County, between San Francisco and Santa Clara counties, and including the cities and towns of Atherton, Belmont, Brisbane, Burlingame, Colma, Daly City, East Palo Alto, El Granada, Foster City, Hillsborough, Half Moon Bay, La Honda, Loma Mar, Los Altos, Menlo Park, Millbrae, Mountain View, Pacifica, Palo Alto, Pescadero, Portola Valley, Redwood City, San Bruno, San Carlos, San Mateo, South San Francisco, and Woodside.