Electron-transfer dissociation is a method of fragmenting multiply-charged gaseous macromolecules in a mass spectrometer between the stages of tandem mass spectrometry. Similar to electron-capture dis
An ion trap mass spectrometer with electron transfer dissociation capability
Collision-induced dissociation, also known as collisionally activated dissociation, is a mass spectrometry technique to induce fragmentation of selected ions in the gas phase. The selected ions are us
Electron-transfer dissociation
…translational modifications (PTM) intact. The technique only works well for higher charge state peptide or polymer ions (z>2). However, relative to collision-induced dissociation (CID), ETD is advantageous for the fragmentation of longer peptides or even entire proteins. This makes the technique important for top-down proteomics…
Collision cell from a Waters Xevo TQ-S triple quadrupole mass spectrometer.