The Elsenz Valley Railway (Elsenztalbahn) or Neckargemünd–Bad Friedrichshall railway is an electrified, partly double-tracked main line in the German state of Baden-Württemberg, running from Heidelberg via Sinsheim to Bad Friedrichshall, that, for part of its course, follows the Elsenz river that gives it its name. The crossing stations on the single-tracked sections were controlled by mechanical signal boxes until 2008, but are now controlled by electronic interlockings.

Heidelberg Hauptbahnhof is the main railway station for the city of Heidelberg. In 2005 it was used by around 42,000 passengers per day and is one of the largest passenger stations in the German state of Baden-Württemberg. The station is classified by Deutsche Bahn as a category 2 station.