The Empire of Nicaea or the Nicene Empire was the largest of the three Byzantine Greek rump states founded by the aristocracy of the Byzantine Empire that fled when Constantinople was occupied by Western European and Venetian armed forces during the Fourth Crusade, a military event known as the Sack of Constantinople. Like the other Byzantine rump states that formed due to the 1204 fracturing of the empire, such as the Empire of Trebizond and the Despotate of Epirus, it was a continuation of the eastern half of the Roman Empire that survived well into the medieval period. A fourth state, known in historiography as the Latin Empire, was established by an army of Crusaders and the Republic of Venice after the capture of Constantinople and the surrounding environs.

The sack of Constantinople occurred in April 1204 and marked the culmination of the Fourth Crusade. Crusader armies captured, looted, and destroyed parts of Constantinople, then the capital of the Byzantine Empire. After the capture of the city, the Latin Empire was established and Baldwin of Flanders was crowned Emperor Baldwin I of Constantinople in the Hagia Sophia.