Enshi Tujia and Miao Autonomous Prefecture is located in the mountainous southwestern corner of Hubei province, People's Republic of China. It forms Hubei's southwestern "panhandle", bordering on Hunan in the south and Chongqing Municipality in the west and northwest. The Yangtze River crosses the prefecture's northeastern corner in Badong County.

The Tujia (Northern Tujia: Bifjixkhar / Bifzixkar, IPA:, Southern Tujia: Mongrzzir, ; Chinese: 土家族; pinyin: Tǔjiāzú; Wade–Giles: Tu3-chia1-tsu2) are an ethnic group and, with a total population of over 8 million, the eighth-largest officially recognized ethnic minority in the People's Republic of China. They live in the Wuling Mountains, straddling the common borders of Hunan, Hubei and Guizhou Provinces and Chongqing Municipality.