The Enzian was a German WWII surface-to-air anti-aircraft missile that was the first to use a radio controlled guidance system. During the missile's development in the late stages of the war it was plagued by organisational problems and was cancelled before becoming operational.
Messerschmitt "Enzian" E-4
The Australian War Memorial's Enzian missile in 2012
Messerschmitt "Enzian" missile (at the background in yellow and red) displayed at RAF museum Cosford
A surface-to-air missile (SAM), also known as a ground-to-air missile (GTAM) or surface-to-air guided weapon (SAGW), is a missile designed to be launched from the ground or the sea to destroy aircraft or other missiles. It is one type of anti-aircraft system; in modern armed forces, missiles have replaced most other forms of dedicated anti-aircraft weapons, with anti-aircraft guns pushed into specialized roles.
A pair of S-300 missiles being launched
A Wasserfall missile lifts off during a test flight.
Nike Ajax was the first operational SAM system.
SA-2 Guideline surface-to-air missiles, one of the most widely deployed SAM systems in the world