Epigenetics
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Epigenetics is the study of changes in gene expression that occur without altering the DNA sequence. The Greek prefix epi- in epigenetics implies features that are "on top of" or "in addition to" the
Activation
Repression
Including medial prefrontal cortex (mPFC)
DNA methylation
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DNA methylation is a biological process by which methyl groups are added to the DNA molecule. Methylation can change the activity of a DNA segment without changing the sequence. When located in a gene
Epigenetics
…relevant alterations to the genome that do not involve mutations in the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Further, non-coding RNA sequences…
Representation of a DNA molecule that is methylated. The two white spheres represent methyl groups. They are bound to two cytosine nucleotide molecules that make up the DNA sequence.