Epinephelus is a genus of marine ray-finned fish, groupers from the subfamily Epinephelinae, part of the family Serranidae, which also includes the anthias and sea basses. They are predatory fish, largely associated with reefs and are found in tropical and subtropical seas throughout the world. They are important target species for fisheries.

Groupers are fish of any of a number of genera in the subfamily Epinephelinae of the family Serranidae, in the order Perciformes.