Epirus is a traditional geographic and modern administrative region in northwestern Greece. It borders the regions of Western Macedonia and Thessaly to the east, West Greece to the south, the Ionian Sea and Ionian Islands to the west and Albania to the north. The region has an area of about 9,200 km2 (3,600 sq mi). It is part of the wider historical region of Epirus, which overlaps modern Albania and Greece but lies mostly within Greek territory.

Western Macedonia is one of the thirteen administrative regions of Greece, consisting of the western part of Macedonia. Located in north-western Greece, it is divided into the regional units of Florina, Grevena, Kastoria, and Kozani. With a population of approximately 255,000 people, as of 2021, the region had one of the highest unemployment rates in the European Union.