The Episcopal Diocese of Indianapolis, formerly known as the Episcopal Diocese of Indiana, is a diocese in Province V of the Episcopal Church. It encompasses the southern two-thirds of the state of Indiana. Its see is in Indianapolis, Indiana, at Christ Church Cathedral. According to the diocesan newsletter, the diocese has 10,137 communicants in 49 parishes. The current bishop is Jennifer Baskerville-Burrows, the first African-American woman to serve as diocesan bishop in the Episcopal Church and the first woman to succeed another woman as a diocesan bishop in the Episcopal Church; Catherine Waynick served as bishop of the diocese from 1997 to 2017.

George Upfold was the first Episcopal Bishop of Indiana after the diocese's division from the Missionary Diocese of the Northwest. He is officially styled, though, as II bishop of Indiana since missionary bishop Jackson Kemper is styled I bishop of Indiana.