Erasmus Hall High School was a four-year public high school located at 899–925 Flatbush Avenue between Church and Snyder Avenues in the Flatbush neighborhood of the New York City borough of Brooklyn. It was founded in 1786 as Erasmus Hall Academy, a private institution of higher learning named for the scholar Desiderius Erasmus, known as Erasmus of Rotterdam, a Dutch Renaissance humanist and Catholic Christian theologian. The school was the first secondary school chartered by the New York State Regents. The clapboard-sided, Georgian-Federal-style building, constructed on land donated by the Flatbush Reformed Dutch Church, was turned over to the public school system in 1896.

Flatbush Avenue is a major avenue in the New York City Borough of Brooklyn. It runs from the Manhattan Bridge south-southeastward to Jamaica Bay, where it joins the Marine Parkway–Gil Hodges Memorial Bridge, which connects Brooklyn to the Rockaway Peninsula in Queens. The north end was extended from Fulton Street to the Manhattan Bridge as "Flatbush Avenue Extension".