Ernest Isley is an American musician, best known as a member of the musical ensemble The Isley Brothers, and also the splinter group Isley-Jasper-Isley.

The Isley Brothers are an American musical group originally from Cincinnati, Ohio, that began as a vocal trio consisting of the brothers O'Kelly Isley Jr., Rudolph Isley and Ronald Isley in the 1950s. With a career spanning over seven decades, the group has enjoyed one of the "longest, most influential, and most diverse careers in the pantheon of popular music".