The Essex Institute (1848–1992) in Salem, Massachusetts, was "a literary, historical and scientific society." It maintained a museum, library, historic houses; arranged educational programs; and issued numerous scholarly publications. In 1992 the institute merged with the Peabody Museum of Salem to form the Peabody Essex Museum.

The Peabody Museum of Salem (1915–1992), formerly the Peabody Academy of Science (1865–1915), was a museum and antiquarian society based in Salem, Massachusetts. The academy was organized in part as a successor to the East India Marine Society, which had become moribund but held a large collection of maritime materials in a museum collection at the East India Marine Hall, built in 1825 on Essex Street. The Peabody Museum was merged with the Essex Institute to form the Peabody Essex Museum in 1992. The East India Marine Hall, now embedded within the latter's modern structure, was designated a National Historic Landmark in 1965 in recognition of this heritage, which represents the nation's oldest continuously-operating museum collection.