Eudokia Makrembolitissa was a Byzantine empress by her successive marriages to Constantine X Doukas and Romanos IV Diogenes. She acted as regent of her minor son, Michael VII in 1067, and resigned her regency by marriage to Romanos IV Diogenes. When he was deposed in 1071 she resumed the regency for her sons, but was soon forced to resign again.

Constantine X Doukas or Ducas, was Byzantine emperor from 1059 to 1067. He was the founder of the Doukid dynasty. During his reign, the Normans took over much of the remaining Byzantine territories in Italy while in the Balkans the Hungarians occupied Belgrade. He also suffered defeats by the Seljuk sultan Alp Arslan.