Euphorbia misera is a semi-succulent shrub in the genus Euphorbia commonly known as the cliff spurge or coast spurge. A drought-deciduous shrub, it is typically found as a gnarled, straggly plant occupying seashore bluffs, hills and deserts. Like other members of its genus, it has a milky sap, which can be found exuding out of the light gray bark when damaged. The alternately-arranged leaves are round and folded in the middle, with small hairs on them. The "flowers" can be found blooming year-round, and are colored maroon or yellow in the center with 5 white to light-yellow petal-like appendages attached outside. This species is native to the Baja California peninsula and Sonora in Mexico, and the coast of southern California in the United States, where it is a rare species. It is threatened in some localities by the development of its coastal habitat, which tends to be prime locations for high-end residential and commercial developments.

Euphorbia is a very large and diverse genus of flowering plants, commonly called spurge, in the family Euphorbiaceae. "Euphorbia" is sometimes used in ordinary English to collectively refer to all members of Euphorbiaceae, not just to members of the genus.