EverQuest is a 3D fantasy-themed massively multiplayer online role-playing game developed by Verant Interactive and 989 Studios for Windows PCs. It was released by Sony Online Entertainment in March 1999 in North America, by Ubisoft in Europe in April 2000. A dedicated version for macOS was released in June 2003, which operated for ten years before being shut down in November 2013. In June 2000, Verant Interactive was absorbed into Sony Online Entertainment, who took over full development and publishing duties of the title. In February 2015, SOE's parent corporation, Sony Computer Entertainment, sold the studio to investment company Inception Acquisitions and was rebranded as Daybreak Game Company, who develops and publishes EverQuest to this day, it was the first commercially successful MMORPG to employ a 3D game engine, its success was on an unprecedented scale. EverQuest has had a wide influence on subsequent releases within the market, holds an important position in the history of massively multiplayer online games.

The game surpassed early subscription expectations and increased in popularity for many years after its release. It has received numerous awards, including the 1999 GameSpot Game of the Year and a 2007 Technology & Engineering Emmy Award. While dozens of similar games have come and gone over the years, EverQuest still endures as a viable commercial enterprise with new expansions still being released on a regular basis twenty years after its initial launch, it has spawned a number of spin-off media, including books and video games, as well a sequel, EverQuest II, which launched in 2004. Many of the elements in EverQuest have been drawn from text-based MUD games DikuMUDs, which in turn were inspired by traditional role-playing games such as Dungeons & Dragons. In EverQuest, players create a character by selecting one of twelve races in the game, which were humans, high-elves, wood-elves, half-elves, dark-elves, barbarians, halflings, gnomes and trolls. In the first expansion, lizard-people were introduced.

Cat-people, frog-people, dragon-people were all introduced in expansions. At creation, players select each character's adventuring occupation, a patron deity, starting city. Customization of the character facial appearance is available at creation. Players move their character throughout the medieval fantasy world of Norrath fighting monsters and enemies for treasure and experience points, optionally mastering trade skills; as they progress, players advance in level, gaining power, prestige and abilities through valorous deeds such as entering overrun castles and keeps, defeating worthy opponents found within, looting their remains. Experience and prestigious equipment can be obtained by completing quests given out by non-player characters found throughout the land. EverQuest allows players to interact with other people through role-play, joining player guilds, dueling other players; the game-world of EverQuest consists of over five hundred zones. Multiple instances of the world exist on various servers.

In the past, game server populations were visible during log-in, showed peaks of more than 3000 players per server. The design of EverQuest, like other massively multiplayer online role-playing games, makes it amenable to cooperative play, with each player having a specific role within a given group. EverQuest featured fourteen playable character classes upon release in 1999, with two others - Beastlord and Berzerker - added in the Shadows of Luclin and Gates of Discord expansions, respectively; each class falls within one of four general categories based on playstyle and the type of abilities they use, with certain classes being restricted to particular races. Melee classes are those which fight at close quarters and use direct physical attacks as opposed to magic; these include the Warrior, a tank-based character which wears heavy armor and is designed to take damage for its group using a taunt ability. Priest classes are healers who learn magic that can mend the wounds of their allies or themselves.

The Priest classes are made up of the Cleric, a specialized support class that wears heavy armor and is adept at healing and strengthening their allies. Casters are sorcerers which wear light armor but command powerful spells; those among them include the Wizard, a specialized damage-dealing class which uses the power of fire and pure magic energy for devastating effect as well as teleportation abilities.

Please add names of notable painters in alphabetical order. Jean Xceron, American abstract painter of Greek origin Xi Gang Xia Chang Xia Gui Xia Shuwen Xia Yong Xiang Shengmo Xiao Yuncong Xie He, Chinese painter, art historian and critic Xie Huan Xie Shichen Xie Sun Xu Beihong, Chinese painter of shuimohua of horses and birds Xu Wei, Ming Dynasty, Chinese painter and dramatist Xu Xi Xuande Emperor Xul Solar, Argentine painter, sculptor and inventor of imaginary languages

Corticotropin-releasing hormone receptor 2 is a protein known by the IUPHAR-recommended name CRF2, encoded by the CRHR2 gene and occurs on the surfaces of some mammalian cells. CRF2 receptors are type 2 G protein-coupled receptors for corticotropin-releasing hormone that are resident in the plasma membranes of hormone-sensitive cells. CRH, a peptide of 41 amino acids synthesized in the hypothalamus, is the principal neuroregulator of the hypothalamic-pituitary-adrenal axis, signaling via guanine nucleotide-binding proteins and downstream effectors such as adenylate cyclase; the CRF2 receptor is a multi-pass membrane protein with a transmembrane domain composed of seven helices arranged in a V-shape. CRF2 receptors are activated by two structurally similar peptides, urocortin II, urocortin III, as well as CRH; the human CRHR2 gene contains 12 exons. Three major functional isoforms, alpha and gamma, encoded by transcripts with alternative first exons, differ only in the N-terminal sequence comprising the signal peptide and part of the extracellular domain.

CRHR2 beta is expressed in human brain. The N-terminal signal peptides of corticotropin-releasing hormone receptor 1 and CRHR2 beta are cleaved off in the endoplasmic reticulum to yield the mature receptors. In contrast, CRHR2 alpha contains a unique pseudo signal peptide, not removed from the mature receptor. In adenylate cyclase activation assays, CRH-related peptides are 10 times more potent at stimulating CRHR2 beta than CRHR2 alpha and CRHR2 gamma, suggesting that the N-terminal sequence is involved in the ligand-receptor interaction. Corticotropin-releasing hormone receptor Receptors, Corticotropin-Releasing Hormone at the US National Library of Medicine Medical Subject Headings Overview of all the structural information available in the PDB for UniProt: Q60748 at the PDBe-KB; this article incorporates text from the United States National Library of Medicine, in the public domain

The 2014–15 Binghamton Bearcats women's basketball team will represent Binghamton University during the 2014–15 NCAA Division I women's basketball season. The Bearcats were led by first year head coach Linda Cimino and play their home games at Binghamton University Events Center, they are members of the America East Conference. They finished the season 4-26, 2-14 in America East play in a tie for an eighth-place finish, they lost in the quarterfinals of the 2015 America East Women's Basketball Tournament to Maine. All home games and conference road games will stream on either AmericaEast.tv. Most road games will stream on the opponents website. All games streamed online. 2014–15 Binghamton Bearcats men's basketball team

Marie is a 1985 American biographical film starring Sissy Spacek as Marie Ragghianti, former head of the Tennessee Board of Pardons and Paroles, removed from office in 1977 after refusing to release prisoners on whose behalf bribes had been paid to aides to Governor Ray Blanton. Ragghianti, a single mother and political appointee, was hounded for refusal to cooperate with the culture of corruption with which she found herself confronted. Two of Blanton's aides faced prosecution for their roles in the scandal; the film was based on the book Marie: A True Story by Peter Maas. The film was directed by Roger Donaldson, with a screenplay by John Briley, best known as the screenwriter of Gandhi, it starred Jeff Daniels, Keith Szarabajka, Morgan Freeman, Fred Thompson, Lisa Banes, John Cullum, Graham Beckel, Macon McCalman. Sissy Spacek as Marie Jeff Daniels as Eddie Sisk Morgan Freeman as Charles Traughber Lisa Banes as Toni Greer Keith Szarabajka as Kevin McCormack Trey Wilson as FBI Agent Fred Thompson as Himself Don Hood as Governor Blanton Most reviewers praised Spacek's performance.

Janet Maslin, writing in the New York Times, said Spacek "...evolves effortlessly from a battered young wife to a self-possessed official, gives yet another guileless, radiant performance of unusual immediacy." Several reviewers praised the performance of Fred Thompson, known as a peripheral figure in the United States Senate probe of the Watergate scandal. Thompson played himself in the film. Marie on IMDb Marie at Rotten Tomatoes Marie at Box Office Mojo Review by Roger Ebert Review in The New York Times

The Pontifical Legation for the Basilicas of Saint Francis and Saint Mary of the Angels in Assisi is the office, vested in a Pontifical Legate, that represents the Holy See in the administration of the Papal minor basilicas in Assisi, namely the Basilica of Saint Francis of Assisi and the Papal Basilica of Saint Mary of the Angels in Assisi. It was founded on 8 August 1969, as the Pontifical Legation for the Basilica of Saint Francis of Assisi. On 21 February 2006, when its responsibilities were changed to include the neighboring Papal Basilica of Saint Mary of the Angels in Assisi, it received its current name. All of the legates to date have been former diplomats. Pontifical Legation for the Basilica of Saint Francis of Assisi Cardinal Silvio Angelo Pio Oddi Cardinal Carlo Furno Cardinal Lorenzo Antonetti Pontifical Legation for the Basilicas of Saint Francis and Saint Mary of the Angels in Assisi Cardinal Attilio Nicora Cardinal Agostino Vallini