FOXP2
Videos
Forkhead box protein P2 is a protein that, in humans, is encoded by the FOXP2 gene. FOXP2 is a member of the forkhead box family of transcription factors, proteins that regulate gene expression by bin
FOXP2 is expressed in the developing cerebellum and the hindbrain of the embryonic day-13.5 mouse. Allen Brain Atlases.
Human FOXP2 gene and evolutionary conservation is shown in a multiple alignment (at bottom of figure) in this image from the UCSC Genome Browser. Note that conservation tends to cluster around coding regions (exons).
2a07: Crystal Structure of Foxp2 bound Specifically to DNA.
2as5: Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.
Neanderthal
Videos
Neanderthals are an extinct group of archaic humans who inhabited Europe and Western and Central Asia during the Middle to Late Pleistocene. Neanderthal extinction occurred roughly 40,000 years ago wi
FOXP2
…arose independently in carnivores and bats. Similar FOXP2 proteins can be found in songbirds, fish, and reptiles such as alligators. DNA sampling from Homo neanderthalensis bones indicates that their FOXP2 gene is a little different though largely similar to those of Homo sapiens (i.e. humans). Previous genetic analysis…
Neanderthal at AMNH
Skullcap of Neanderthal 1, the type specimen, at the Musée de l'Homme, Paris
The site of Kleine Feldhofer Grotte where Neanderthal 1 was discovered
William K. Gregory's The Family Tree of Man exhibit at the American Museum of Natural History, 1924 1) Notharctus 2) Propliopithecus 3) Dryopithecus 4) Java Man 5) Piltdown Man 6) Heidelberg Man 7) Neanderthal Man 8) Cro-Magnon Man 9) Australian Black-fellow (pejorative term for Aboriginal Australians) 10) Hottentot (pejorative term for the Southern African Khoisan) 11) Chinese 12) American Caucasian