Parts of F Street and 7th Street, N.W. and nearby blocks have historically been the heart of the Washington, D.C. Downtown shopping district. In the first half of the 20th century there were numerous upscale large department stores along and near F Street, while 7th Street housed more economical emporia and large retail furniture stores. The F street corridor stretches west from Downtown's Penn Quarter and Gallery Place towards 15th Street, while the 7th Street corridor includes the neighborhoods of Penn Quarter, Chinatown and Mount Vernon Square, and extends up to the border of Shaw.

Downtown is the central business district of Washington, D.C., located in Northwest D.C. It is the third largest central business district in the United States. The "Traditional Downtown" has been defined as an area roughly between Union Station in the east and 16th Street NW in the west, and between the National Mall on the south and Massachusetts Avenue on the north, including Penn Quarter. However, nowadays, Downtown D.C. usually refers to a larger area, as the DC Office of Planning states:…most residents, workers, and visitors think of Downtown in a broader sense — including areas as far north as Dupont Circle, as far west as Foggy Bottom, and as far east as Capitol Hill. Only about half of the central city workforce is located within the city’s traditional Downtown.