Farm to Market Road 50 is a Farm to Market Road in the U.S. state of Texas maintained by the Texas Department of Transportation (TxDOT). The 52.9-mile (85.1 km) route begins at State Highway 105 near Brenham and passes to the north through Independence to U.S. Route 79 and U.S. Route 190 near Hearne. The road has a brief concurrency with SH 21 along a bridge crossing the Brazos River. The road is in Washington, Burleson, Brazos, and Robertson counties.

Independence is an unincorporated community in Washington County, Texas, United States. According to the Handbook of Texas, the community had a population of 140 in 2000. It is located about an hour northwest of the Greater Houston metropolitan area.