Fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic trematode of the class Trematoda, phylum Platyhelminthes. It infects the livers of various mammals, including humans, and is transmitted by sheep and cattle to humans all over the world. The disease caused by the fluke is called fasciolosis or fascioliasis, which is a type of helminthiasis and has been classified as a neglected tropical disease. Fasciolosis is currently classified as a plant/food-borne trematode infection, often acquired through eating the parasite's metacercariae encysted on plants. F. hepatica, which is distributed worldwide, has been known as an important parasite of sheep and cattle for decades and causes significant economic losses in these livestock species, up to £23 million in the UK alone. Because of its relatively large size and economic importance, it has been the subject of many scientific investigations and may be the best-known of any trematode species. F. hepatica's closest relative is Fasciola gigantica. These two flukes are sister species; they share many morphological features and can mate with each other.
Fasciola hepatica
A simple diagram to show the difference between the teguments of free-living and parasitic flatworms: a. shows the syncytial epithelial tegument found in parasitic flatworms, such as F. hepatica. b. shows the multicellular, nonsyncytial, epithelia, found in nonparasitic, free-living flatworms.
Diagram of the main organ systems of F. hepatica throughout the progressive life stages of the fluke (1938). A - egg; B - miracidium; C - sporocyst; D - rediae, E - immature cercaria, F - cercaria, G - encysted stage, H - adult fluke (nervous and reproductive systems omitted)
Fasciola hepatica prevalence. The countries in red are those with high prevalence, those in orange have low-medium prevalence.
Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way of life. The entomologist E. O. Wilson characterised parasites as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes.
A fish parasite, the isopod Cymothoa exigua, replacing the tongue of a Lithognathus
Head (scolex) of tapeworm Taenia solium, an intestinal parasite, has hooks and suckers to attach to its host
The parasitic castrator Sacculina carcini (highlighted) attached to its crab host
Human head-lice are directly transmitted obligate ectoparasites