The Feast of the Most Precious Blood of Our Lord Jesus Christ was in the General Roman Calendar from 1849 to 1969. It was focused on the Blood of Christ and its salvific nature.

Blood of Christ, also known as the Most Precious Blood, in Christian theology refers to the physical blood actually shed by Jesus Christ primarily on the Cross, and the salvation which Christianity teaches was accomplished thereby, or the sacramental blood (wine) present in the Eucharist or Lord's Supper, which some Christian denominations believe to be the same blood of Christ shed on the Cross.