Fergana, or Ferghana, is a district-level city and the capital of Fergana Region in eastern Uzbekistan. Fergana is about 420 km east of Tashkent, about 75 km southwest of Andijan, and less than 20 km from the Kyrgyzstan border. The modern city was founded in 1876.

Fergana Region is one of the regions of Uzbekistan, located in the southern part of the Fergana Valley in the far east of the country. It borders the Namangan and Andijan Regions of Uzbekistan, as well as Kyrgyzstan and Tajikistan. Its capital is the city of Fergana. It covers an area of 6,760 km2. The population is approximately 4,014,895 as of 2023, with 45% of the population living in rural areas.