The Ferrari 275 is a series of front-engined V12-powered grand touring automobiles with two-seater coupé and spider bodies produced by Ferrari between 1964 and 1968. The first 275 series cars were powered by a 3.3 L (3286 cc) overhead camshaft Colombo 60° V12 engine producing 260–320 hp (190–240 kW). An updated 275 GTB/4 was introduced in 1966, with a revised four overhead camshaft engine producing 300 hp (220 kW). The 275 series were the first road-going Ferraris equipped with a transaxle and independent rear suspension.

The Ferrari Colombo Engine was a petrol fueled, water cooled, carburetted 60° V12 engine designed by Gioacchino Colombo and produced in numerous iterations by Italian automaker Ferrari between 1947 and 1988. The maker's first homegrown engine, its linear successor is the Lampredi V12, which it far outlived, the last Lampredi being made in 1959.