Fifth Street is a census-designated place (CDP) located in the extraterritorial jurisdiction of Stafford within Fort Bend County, Texas, United States. The population was 2,284 at the 2020 census. Fifth Street is within the ZIP code 77477. Therefore, residents of Fifth Street have an address of Stafford, Texas.

Stafford is a city in the U.S. state of Texas, in the Houston–The Woodlands–Sugar Land metropolitan area. The city is mostly in Fort Bend County, with a small part in Harris County. As of the 2020 census, Stafford's population was 17,666, down from 17,693 at the 2010 census.